• 专利附录
  • 专利说明
  • 权利要求
  • 类似技术
  • 同族专利
  • 引用文献
  • 法律状态
  • 优先权
    • 专利摘要:
    Devices are provided to test, identify and compensate for eye pathologies that affect a patient's vision in the form of digital therapeutic corrective glasses that provide personalized visual correction / enhancement. The devices include wearable glasses with one or more digital monitors that are used to recreate an entire visual field as a scanned corrected image or that include custom reality glasses that can be used to overlay a visual scene with an image generated to correct or enhance the visual field of the patient.
    公开号:BR112020006142A2
    申请号:R112020006142-5
    申请日:2018-09-27
    公开日:2020-11-24
    发明作者:Mohamed Abou Shousha
    申请人:University Of Miami；
    IPC主号:
    专利说明:

    [0001] [0001] This application claims the benefit of US Provisional Application No. 62 / 563,770, entitled "Digital Therapeutic Corrective Glasses", filed on September 27, 2017, which is incorporated into this document by reference in its entirety. FIELD OF THE INVENTION
    [0002] [0002] The present disclosure refers to techniques to compensate visual impairments in the visual field, visual aberrations and visual alignment errors of a user and, more particularly, to wearable devices that correct the visual deficiencies mentioned above and provide corrections to users. BACKGROUND
    [0003] [0003] The description of the background provided in this document is intended to generally present the context of the disclosure. The work of the currently named inventors, as described in this background section, as well as aspects of the description that would not otherwise qualify as the state of the art at the time of filing, are not expressly or implicitly admitted as a state against the present disclosure.
    [0004] [0004] Patients with ocular pathologies, such as pathologies of the optic nerve and / or pathologies of the retina (for example, patients with glaucoma) exhibit variable localized reduction in the visual sensitivity of their visual field. This means that, in some areas of your visual field, the image is darker than in other areas. This darkening in the visual field results because more intense lighting is needed to stimulate the eye in the affected areas compared to the unaffected areas and is the result of ocular pathology. Patients will describe this darkening as having a cloud or a blur over a part of their visual field. When the pathology progresses, the affected areas of the visual field may increasingly lose their ability to see and, eventually, become totally blind.
    [0005] [0005] The visual field diagnostic devices were used to test the sensitivity of a patient's visual field, projecting a light that is initially weak and then, if the patient does not indicate that he is seeing, the intensity increases more and more until the patient indicates that he / she sees the light. The sensitivity of the projected area is then recorded. If the patient does not see the light, even with the maximum intensity of illumination, that area of the visual field is identified as blind.
    [0006] [0006] Refractive errors negatively affect vision. These refractive errors are caused by irregularities in the refractive elements of the eye. They result in blurred vision, which is partially corrected by glass glasses and contact lenses. This is the reason why some patients see more than others and some have better quality of vision than others. Glasses made of glass, as well as contact lenses, come only in certain increments and correct only regular refractive errors, for example, regular astigmatism. These regular refractive errors are called low-order aberrations. High-order aberrations are refractive errors that cannot be corrected by glasses or contact lenses. In addition, high-order aberrations are dynamic and not fixed. They change according to the size of the pupil, the state of accommodation of the eyes and the direction of the look.
    [0007] [0007] Current techniques for the treatment of presbyopia include single-vision, bifocal and multifocal reading glasses and multifocal contact lenses. With multifocal or bifocal glasses, the patient will look through specific areas of the glass to obtain the necessary correction. With multifocal contact lenses, light is diffracted at multiple focal points, improving the depth of focus, but at the expense of decreased quality of vision. All of these techniques are not very convenient and limit your near vision.
    [0008] [0008] Double vision results from misalignment of the patient's line of sight. The double vision is dynamic and not static, which means that it increases and decreases towards one or multiple looks. Therefore, if the patient has limitations in bringing the right eye out, double vision will increase when the patient is looking to the right and may decrease when the patient is looking to the left.
    [0009] [0009] Anisometropia (uneven refractive error in both eyes of a patient) is not uncommon, especially after eye surgery or trauma. It is one of the indications for cataract surgery by Medicare. Corrective glass glasses are not able to correct anisometropia. This is because corrective glass glasses produce two images, one for each eye, with unequal sizes (aniseiconia) and the brain cannot fuse these two images into a single binocular view. This problem is simply because the lenses of glass glasses are convex, enlarge the image, or concave, minimize the image. The amount of enlargement or minification depends on the amount of correction.
    [0010] [0010] The lenses of glass glasses are convex, enlarge the image, or concave, minimize the image. This affects the patients' visual field. The glass glasses correct the patient's refractive error, but they also produce distortions in the image being viewed.
    [0011] [0011] Patients with anisocoria have uneven pupil size and can be congenital, acquired from an eye disease or after surgery or trauma. These patients have sensitivity to light in a single eye and that eye cannot tolerate the brightness of light tolerated by the healthy eye.
    [0012] [0012] It is necessary an optical device that can compensate for the visual deficiencies mentioned above. SHORT DESCRIPTION
    [0013] [0013] In exemplary modalities, the present techniques provide devices to test, identify and / or compensate for one or more ocular pathologies that affect a patient's vision. Such ocular pathologies include, for example, pathologies of the optic nerve, such as glaucoma, optic neuritis and optic neuropathies, pathologies of the retina, such as macular degeneration, retinitis pigmentosa, pathologies of the visual pathway, such as strokes and microvascular tumors and other conditions, such as presbyopia, strabismus, high and low optical aberrations, monocular vision, anisometropia and aniseiconia, sensitivity to light, anisocorean refractive errors and astigmatism. In some exemplary embodiments, the present techniques provide devices to improve a field of view for a patient, such as modifying: a horizontal, vertical and / or diagonal angle of view; light supplied to one or more regions; size of objects in one or more regions; and / or location of objects in one or more regions.
    [0014] [0014] In exemplary embodiments, the systems and devices described in this document may include a wearable glasses device configured to test, identify, compensate for visual impairments and / or improve aspects of a patient's vision or field of vision. Some of these modalities can be configured to provide personalized customized visual correction to the patient who uses them. In one example, the spectacle device comprises digital therapeutic corrective spectacles (also referred to herein as "OTD"). Glasses may also include, for example, glasses and sunglasses.
    [0015] [0015] In one aspect, a vision system can include a wearable glasses device. The system may further include an image processing device having a processor and a memory. The image processing device can store instructions in memory, where the instructions, when executed, cause the processor to execute a test mode and / or a vision mode.
    [0016] [0016] In one example, the system may also include a pupil tracking sensor configured to track a physical condition of a patient's pupil and / or line of sight. In an additional example, the pupil tracking sensor comprises one or more image sensors directed inward. In the example above or in another example, the system can include a field of view sensor configured to capture a field of view in view mode.
    [0017] [0017] In any of the examples above or another, the instructions, when executed by the processor, may cause the processor, in a test mode, (i) to instruct a display by the wearable glasses device of a plurality of stimuli from test the patient on one or more test sites in a visual test field, (ii) instruct the inward-directed image sensor to capture indications of the position of the pupil's physical condition and / or line of sight when displaying the plurality of test stimuli at one or more test sites, and (iii) determine one or more affected regions in the visual field of test and determine one or more pathologies of the patient's vision, in which the plurality of stimuli differ in contrast levels with each other and in relation to a baseline contrast level.
    [0018] [0018] In any of the examples above or another, the instructions when executed by the processor can cause the processor, in the view mode, to correct the image of the field of view to improve a field of view and / or compensate for one or more more affected regions and instruct a display by the wearable glasses device of the corrected image to the patient using the wearable glasses device.
    [0019] [0019] In either of the examples above or another, the image processing device stores instructions that, when executed, cause the processor: in vision mode, to instruct the field of view camera to capture the image of the visual field , process the image in response to one or more affected regions in the test visual field, correct the image to compensate for one or more affected regions and instruct a display by the wearable glasses device of the corrected image to the patient as a digital image.
    [0020] [0020] In either of the examples above or another, the digital glasses may further comprise a first digital monitor and a second digital monitor, each configured to display one of the plurality of stimuli for a respective eye of the patient in the test mode. In either of the above or other examples, the field of view camera comprises a first field of view camera and a second field of view camera, the first field of view camera corresponding to the first digital monitor and the second field camera corresponding to the second digital monitor. In either of the above or other examples, the physical condition of the pupil is selected from one or more of (i) pupil movement of one or more pupils, (ii) a limbus, (iii) a line of sight and / or (iv) a visual axis of the patient. In either of the above or other examples, the field of view camera comprises at least one field of view camera that extends inwardly from an outer surface of the wearable glasses. In either of the above or other examples, the field of view camera comprises at least one field of view camera that extends outwardly from an outer surface of the wearable glasses. In either of the above examples or the other, in the view mode, the field of view camera captures continuous images of the visual field.
    [0021] [0021] In any of the above or other examples, the plurality of test stimuli comprises at least one text test image or an object. In any of the above or other examples, one or more affected regions comprise regions with reduced vision sensitivity or major or minor optical aberrations. In either of the above or other examples, the one or more affected regions comprises regions of reduced brightness. In either of the above or other examples, the plurality of stimuli differs in contrast levels from each other and from a baseline contrast level by at least 20 dB. In either of the above or other examples, the plurality of stimuli differs in contrast levels from each other and from a baseline contrast level of at least 30 dB. In either of the above or other examples, the image processing device stores instructions that, when executed, cause the processor to: in test mode, instruct a display by the wearable glasses device of the plurality of test stimuli to the patient in a downward or upward contrast.
    [0022] [0022] In another aspect, a vision system includes a wearable glasses device, at least a digital monitor, at least one field of view camera and an image processing device.
    [0023] [0023] In some examples, at least one digital monitor is configured to display an image to a patient's eye. In one example, at least one field of view camera can be configured to capture a plurality of monocular images of a scene, each monocular image being displaced from one another. In one example, the image processing device can include a processor and memory and can be coupled to at least one digital monitor. The image processing device can store instructions in memory which, when executed, cause the processor to combine the plurality of monocular images into an image combined with a field of view larger than a field of view of any of the plurality of monocular images . In any of the above modes or in another mode, the instructions can cause the processor to display the combined image on at least one digital monitor to present the patient with an enlarged field of view of the scene.
    [0024] [0024] In any of the examples above or another, the image processing device stores instructions in memory that, when executed, cause the processor to: combine the plurality of monocular images in the combined image, performing selective field shift in at least at least one of the plurality of monocular images in relation to the other plurality of monocular images to generate an enlarged peripheral region for the combined image. In either of the above or other examples, the image processing device stores instructions in memory that, when executed, cause the processor to: combine the plurality of monocular images in the combined image, performing peripheral selective field manipulation in at least one the plurality of monocular images in relation to the other plurality of monocular images.
    [0025] [0025] In either of the examples above or another, manipulation of the peripheral selective field comprises the realization of a shrinkage or enlargement in a peripheral region or in a central macular region of the plurality of monocular images. In either of the above or other examples, the image processing device stores instructions in memory that, when executed, cause the processor to: combine the plurality of monocular images in the combined image, identifying a defective field region in at least one of the plurality of monocular images, capturing the defective field region and transferring the captured defective field region to a defective field region and forming the combined image to include the captured defective field region transferred for display to the patient .
    [0026] [0026] In either of the examples above or another, the image processing device stores instructions in memory that, when executed, cause the processor to: combine the plurality of monocular images in the combined image, identifying a common central region of each one of the plurality of monocular images and identifying peripheral regions diverging from the plurality of monocular images; and form the combined image to have a first region corresponding to the common central region and a second region formed by combining the divergent peripheral regions in an enlarged peripheral region that surrounds the first region. In either of the examples above or in another example, the image processing device stores instructions in memory that, when executed, cause the processor to: form the combined image so that the second region corrects aberrations and defects in the visual field of a patient's eye. In either of the above or other examples, the at least one digital monitor comprises a first digital monitor and a second digital monitor, each configured to display the combined image for a respective patient's eye.
    [0027] [0027] In either of the examples above or another, the image processing device stores instructions in memory that, when executed, cause the processor to perform a fisheye transformation in a first region of the plurality of monocular images to modify a radial component of the plurality of monocular images, according to:
    权利要求:
    Claims (30)
    [1]
    1. System, characterized by the fact that it comprises: a wearable glasses device with a housing and a screen configured to display an image to at least one eye of a patient during a vision mode; an image sensor directed inwards, attached to the wearable glasses device and configured to track a physical condition of the patient's pupil and / or line of sight; an outward-facing field of view camera, configured to capture a field of view of the patient's field of view during vision mode; and an image processing device with a processor and memory, the image processing device storing instructions in memory, where the instructions, when executed, cause the processor: in a test mode, (i) to instruct the screen displaying a plurality of test stimuli for the patient at one or more test sites through a visual test field, (ii) instruct the image sensor directed inward to capture position indications of the pupil's physical condition and / or line of sight when displaying the plurality of test stimuli, and (iii) determine one or more affected regions in the visual field of test and determine one or more pathologies of the patient's vision, in which the plurality of stimuli differs in levels of contrast with each other and in relation to a baseline contrast level; and / or in vision mode, correct the image to improve the field of view and / or compensate for one or more affected regions and instruct the screen to display the corrected image to the patient using the wearable glasses device.
    [2]
    2. System, according to claim 1, characterized by the fact that the image processing device stores instructions that, when executed, cause the processor to:
    in view mode, instruct the field of view camera to capture the image from the visual field, process the image in response to one or more affected regions in the test visual field, correct the image to compensate for one or more affected regions, and instruct a display, by the wearable glasses device, of the corrected image to the patient, as a digital image.
    [3]
    3. System, according to claim 1, characterized by the fact that digital glasses also comprise a first digital monitor and a second digital monitor, each configured to display one of the plurality of stimuli for a patient's respective eye in the mode of test.
    [4]
    4. System according to claim 3, characterized by the fact that the field of view camera comprises a first field of view camera and a second field of view camera, the first field of view camera corresponding to the first monitor digital camera and the second field of view camera corresponding to the second digital monitor.
    [5]
    5. System according to claim 1, characterized by the fact that the physical condition of the pupil is (i) pupil movement of one or more pupils, (ii) a limbus, (iii) a line of sight and / or (iv) a visual axis of the patient.
    [6]
    6. System according to claim 1, characterized by the fact that the field-of-view camera comprises at least one field-of-view camera that extends inwards from an internal surface of the wearable glasses.
    [7]
    7. System according to claim 1, characterized by the fact that the field of view camera comprises at least one field of view camera that extends outwardly from an external surface of the wearable glasses.
    [8]
    8. System, according to claim 1, characterized by the fact that, in the view mode, the field of view camera captures continuous images of the visual field.
    [9]
    9. System according to claim 1, characterized by the fact that the plurality of test stimuli comprises at least one text test image or an object.
    [10]
    10. System according to claim 1, characterized by the fact that the one or more affected regions comprise regions with reduced vision sensitivity or greater or lesser optical aberrations.
    [11]
    11. System according to claim 1, characterized by the fact that the one or more affected regions comprise regions of reduced brightness.
    [12]
    12. System according to claim 1, characterized by the fact that the plurality of stimuli differ in contrast levels between themselves and in relation to a baseline contrast level of at least 20 dB.
    [13]
    13. System according to claim 1, characterized by the fact that the plurality of stimuli differ in contrast levels between themselves and in relation to a baseline contrast level of at least 30 dB.
    [14]
    14. System according to claim 1, characterized by the fact that the image processing device stores instructions that, when executed, cause the processor: in test mode, to instruct a display by the wearable glasses device of the plurality of test stimuli to the patient in downward or upward contrast.
    [15]
    15. System, characterized by the fact that it comprises: a wearable glasses device with at least one digital monitor configured to display an image to a patient's eye; at least one field-of-view camera configured to capture a plurality of monocular images of a scene, each monocular image being displaced from one another;
    an image processing device with a processor and memory, and coupled to at least one digital monitor, the image processing device storing instructions in memory, where the instructions, when executed, cause the processor to: combine the plurality monocular images in an image combined with a field of view larger than a field of view of any of the plurality of monocular images; and display the combined image on at least one digital monitor to present the patient with an enlarged field of view of the scene.
    [16]
    16. System, according to claim 15, characterized by the fact that the image processing device stores instructions in memory that, when executed, cause the processor to: combine the plurality of monocular images in the combined image, performing displacement of selective field in at least one of the plurality of monocular images in relation to the other plurality of monocular images to generate an enlarged peripheral region for the combined image.
    [17]
    17. System, according to claim 15, characterized by the fact that the image processing device stores instructions in memory that, when executed, cause the processor to: combine the plurality of monocular images in the combined image, performing manipulation of peripheral selective field in at least one of the plurality of monocular images in relation to the other plurality of monocular images.
    [18]
    18. The system according to claim 17, characterized by the fact that the manipulation of the peripheral selective field comprises the realization of a shrinkage or enlargement in a peripheral region or in a central macular region of the plurality of monocular images.
    [19]
    19. System, according to claim 15, characterized by the fact that the image processing device stores instructions in memory that, when executed, cause the processor to: combine the plurality of monocular images in the combined image, identifying a region defective field in at least one of the plurality of monocular images, capturing the defective field region and transferring the captured defective field region to a defective field region and forming the combined image to include the defective field region captured transferred for display to the patient.
    [20]
    20. System, according to claim 15, characterized by the fact that the image processing device stores instructions in memory that, when executed, cause the processor to: combine the plurality of monocular images in the combined image, identifying a region common core of each of the plurality of monocular images and identifying peripheral regions diverging from the plurality of monocular images; and form the combined image to have a first region corresponding to the common central region and a second region formed by combining the divergent peripheral regions in an enlarged peripheral region that surrounds the first region.
    [21]
    21. System, according to claim 20, characterized by the fact that the image processing device stores instructions in memory that, when executed, cause the processor to: form the combined image so that the second region corrects aberrations and defect of the visual field of a patient's eye.
    [22]
    22. System according to claim 20, characterized in that the at least one digital monitor comprises a first digital monitor and a second digital monitor, each configured to display the combined image for a respective patient's eye.
    [23]
    23. Apparatus, characterized by the fact that it comprises: a wearable glasses device, the wearable glasses device with at least one optical element to pass an image of a scene visible to the patient, the wearable glasses device with still at least one digital monitor corresponding to at least one optical element, the at least one digital monitor being configured to superimpose a corrective image element on an image of the visible scene of the at least one optical element; and an image processing device, with a processor and a memory, and coupled to at least one digital monitor, the image processing device configured to: generate the corrective image element as a peripheral element of the visible scene image to correct a defect in the peripheral visual field or generate the corrective image element as a central element of the visible scene image to correct a central visual defect; and displaying the corrective image element on the scene visible to the patient.
    [24]
    24. Apparatus according to claim 23, characterized in that the corrective image element is an adjusted intensity of the peripheral element in relation to a central image region of the visible scene or an adjusted intensity of the central element in relation to a peripheral image region of the visible scene.
    [25]
    25. Apparatus according to claim 23, characterized by the fact that the image processing device is configured to: adjust the position and / or composition of the corrective image element in response to the detected movement of the patient's eye.
    [26]
    26. Apparatus according to claim 23, characterized by the fact that the image processing device is configured for:
    identify one or more affected regions of one or both of the patient's eyes; and determining the corrective imaging element that compensates for one or more affected regions.
    [27]
    27. Apparatus according to claim 23, characterized by the fact that the image processing device is configured to: in a test mode, (i) instruct at least one digital monitor to display a plurality of test stimuli to the patient at one or more test sites in a visual test field, (ii) instruct an image sensor of the device to capture the position indications of the pupil's physical condition and / or line of sight during the display of the plurality of stimuli test at one or more test sites and (iii) determine one or more affected regions in the visual field of test and determine one or more pathologies of the patient's vision.
    [28]
    28. Apparatus according to claim 27, characterized by the fact that the plurality of stimuli differ in contrast levels between themselves and in relation to a baseline contrast level.
    [29]
    29. Apparatus according to claim 23, characterized by the fact that the at least one digital monitor is contained with a layer of the at least one optical element.
    [30]
    30. Apparatus according to claim 23, characterized in that the layer is an inner layer or an outer layer of at least one optical element.
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    法律状态:
    2021-12-07| B350| Update of information on the portal [chapter 15.35 patent gazette]|
    优先权:
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    US201762563770P| true| 2017-09-27|2017-09-27|
    US62/563,770|2017-09-27|
    PCT/US2018/053213|WO2019067779A1|2017-09-27|2018-09-27|Digital therapeutic corrective spectacles|
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